LGVH - Biorepository - BLCL Collection

LGVH Reference Cell-line Collection

Throughout the past years, LGVH research proyects have allowed us to compile several collections of biological specimens from both healthy individuals and those affected by specific diseases. These specimens include genomic and mitochondrial DNA's, blood serum, peripheral-blood mononuclear cells and in some cases RNA and B-Lymphoblastoid cell-lines. In the case of viral diseases, viable replication competent viral particles might also be available. All samples are provided with associated ethnographic, demographic and clinical information where available. All of the biological specimens mentioned herein have been anonymized in order to protect donor confidentiality, as such, donor tracking is not possible. All samples were obtained following our local institution's Ethics Review Board Guidelines.

Samples are distributed free-of charge to researchers involved in the study of human immune gene polymorphism, diversity and clinical or biological relevance. Other genetic systems will also be considered as long as the proposing researcher provides and executive summary of the project for proper ethics clearence (and only for some collections for which informed consent can be readily obtained). Preference will be given to Mexican nationals and to those seeking to address national healthy priorities or diseases of national epidemiological relevance. Researchers for whom approval of biospecimen use is granted are only asked to include information on the source of the collection in either the "Materials & Methods" or "Acknowledgments" sections of the corresponding publication. In addition, all information derived from genetic testing, profiling or characterisation of these specimens should be made available for inclusion in this database. Researchers interested in obtaining aliquots of these samples for research use should contact us via eMail (lgvh.uaslp@gmail.com).

Click on the images to the right of the captions to view or download the associated file.

Epstein-Barr Virus (EBV)-Transformed B-Lymphoblastoid Cell-Lines

Reference cell-lines generated by Laboratorio de Genómica Viral y Humana. Facultad de Medicina, Universidad Autónoma de San Luis Potosí.

MX-REF-DMHP Epstein-Barr Virus (EBV)-transformed B-Lymphoblastoid cell line generated from peripheral blood cells isolated from a Mexican mestizo donor as a source of reference genomic DNA for molecular method optimizations. Species: Homo sapiens Sex: Female Source tissue: Peripheral blood lymphocytes Karyotype: 46, XX View cell line specifications and microphotographs.
MX-REF-SEGP Epstein-Barr Virus (EBV)-transformed B-Lymphoblastoid cell line generated from peripheral blood cells isolated from a Mexican mestizo donor as a source of reference genomic DNA for molecular method optimizations. Species: Homo sapiens Sex: Male Source tissue: Peripheral blood lymphocytes Karyotype: 46, XY View cell line specifications and microphotographs.
MX-REF-CAGS Epstein-Barr Virus (EBV)-transformed B-Lymphoblastoid cell line generated from peripheral blood cells isolated from a Mexican mestizo donor as a source of reference genomic DNA for molecular method optimizations. Species: Homo sapiens Sex: Male Source tissue: Peripheral blood lymphocytes Karyotype: 46, XY View cell line specifications and microphotographs.
MX-TNK (Amerindian Reference Collection) Epstein-Barr Virus (EBV)-transformed B-Lymphoblastoid cell line generated from peripheral blood cells isolated from Mexican Tenek Amerindian donors compiled as part of the anthropological collection of Mexican amerindian specimens. Species: Homo sapiens Sex: Mostly female donors Source tissue: Peripheral blood lymphocytes Karyotype: 46,XX and 46,XY View cell line list, specifications and microphotographs.
B95-8 The B95-8 marmoset cell line produces high titers of infectious EBV. It should be handled in a BSL2 facility and treated as a biohazardous agent. Species: Homo sapiens Sex: Male Source tissue: Peripheral blood lymphocytes Karyotype: 46, XY View cell line specifications and microphotographs.
Hep-G2 The Hep-G2 cell line is a suitable in vitro model system for the study of polarized human hepatocytes. HepG2 cells are a suitable model to study the intracellular trafficking and dynamics of bile canalicular and sinusoidal membrane proteins and lipids in human hepatocytes in vitro. Species: Homo sapiens Sex: Male Source tissue: Well-differentiated hepatocellular carcinoma Karyotype: 55, XY View cell line specifications and microphotographs.