Epstein-Barr Virus (EBV)-Transformed B-Lymphoblastoid Cell-Lines
Reference cell-lines generated by Laboratorio de Genómica Viral y Humana.
Facultad de Medicina, Universidad Autónoma de San Luis Potosí.
The deficiency of positive control material for molecular genetic testing has been identified as
an issue of utmost urgency for clinical genetic testing. Molecular genetic testing is an
important component of routine health care as the genetic foundations of a growing
number of diseases are revealed. In addition studies of human population genetics and diversity
have suffered from the lack of suitable, well-characterized biological specimens. The availability
of positive control material for performance evaluation and quality assurance of existing tests
and molecular assays as well as for development and validation of novel tests, is critical to the
genetic testing community. Reliable, high-quality control material for genetic testing can be
provided by stably transformed B-lymphocyte cell lines derived from blood from reference subjects
or those bearing genetic, ethnical or clinical features of interest. Lymphoblastoid cell lines are
used extensively by proficiency testing groups, and many cell lines of this type are available
in our repository.
MX-TNK-0068
Age and sex: 40 year old female donor sample
Ancestry: Tenek amerindian ancestry documented for 2 previous generations
Sampled on: 13/Feb/2009
Source: ACD-anticoagulated peripheral blood lymphocyte's
Site: Tamuin, San Luis Potosí. Mexico
Clinical history: Arterial hypertension and maternal history of T2DM.
View MX-TNK-0068 cell-line transformation log |
Culture microphotograph after transformation
MX-TNK-0069
Age and sex: 57 year old female donor sample
Ancestry: Tenek amerindian ancestry documented for 3 previous generations
Sampled on: 13/Feb/2009
Source: ACD-anticoagulated peripheral blood lymphocyte's
Site: Tamuin, San Luis Potosí. Mexico
Clinical history:T1DM
View MX-TNK-0069 cell-line transformation log |
Culture microphotograph after transformation
MX-TNK-0070
Age and sex: 44 year old female donor sample
Ancestry: Tenek amerindian ancestry documented for 3 previous generations
Sampled on: 13/Feb/2009
Source: ACD-anticoagulated peripheral blood lymphocyte's
Site: Tanlajas, San Luis Potosí. Mexico
Clinical history: None.
View MX-TNK-0070 cell-line transformation log |
Culture microphotograph after transformation
MX-TNK-0071
Age and sex: 36 year old female donor sample
Ancestry: Tenek amerindian ancestry documented for 3 previous generations
Sampled on: 13/Feb/2009
Source: ACD-anticoagulated peripheral blood lymphocyte's
Site: Tamuin, San Luis Potosí. Mexico
Clinical history: Maternal history of renal disease.
View MX-TNK-0071 cell-line transformation log |
Culture microphotograph after transformation
MX-TNK-0072
Age and sex: 20 year old female donor sample
Ancestry: Tenek amerindian ancestry documented for 3 previous generations
Sampled on: 13/Feb/2009
Source: ACD-anticoagulated peripheral blood lymphocyte's
Site: Tamuin, San Luis Potosí. Mexico
Clinical history:Maternal history of T2DM.
View MX-TNK-0072 cell-line transformation log |
Culture microphotograph after transformation
MX-TNK-0073
Age and sex: 28 year old female donor sample
Ancestry: Tenek amerindian ancestry documented for 3 previous generations
Sampled on: 13/Feb/2009
Source: ACD-anticoagulated peripheral blood lymphocyte's
Site: Tamuin, San Luis Potosí. Mexico
Clinical history: Maternal history of acute myocardial infarction.
View MX-TNK-0073 cell-line transformation log |
Culture microphotograph after transformation
MX-TNK-0074
Age and sex: 28 year old female donor sample
Ancestry: Tenek amerindian ancestry documented for 3 previous generations
Sampled on: 13/Feb/2009
Source: ACD-anticoagulated peripheral blood lymphocyte's
Site: El Colorado Tamuin, San Luis Potosí. Mexico
Clinical history: T2DM and acute myocardial infarction, maternal history of T2DM.
View MX-TNK-0074 cell-line transformation log |
Culture microphotograph after transformation
MX-TNK-0075
Age and sex: 35 year old female donor sample
Ancestry: Tenek amerindian ancestry documented for 3 previous generations
Sampled on: 13/Feb/2009
Source: ACD-anticoagulated peripheral blood lymphocyte's
Site: Tampacoy Tamuin, San Luis Potosí. Mexico
Clinical history: Arterial hypertension and maternal and Maternal great-grandmother history of T2DM.
View MX-TNK-0075 cell-line transformation log |
Culture microphotograph after transformation
MX-TNK-0076
Age and sex: 46 year old male donor sample
Ancestry: Tenek amerindian ancestry documented for 2 previous generations
Sampled on: 13/Feb/2009
Source: ACD-anticoagulated peripheral blood lymphocyte's
Site: Tampacoy Tamuin, San Luis Potosí. Mexico
Clinical history: Arterial hypertension.
View MX-TNK-0076 cell-line transformation log |
Culture microphotograph after transformation