Hantavirus and rodent-borne viruses

In the last 6 years, our lab has participated in studying rodent-borne viral threats present in wild Mexican rodents. Initial research aimed to establish whether the new world hantavirus Sin Nombre Virus was present in Peromyscus maniculatus populations of the state of Sonora, Queretaro and San Luis Potosí.

Current efforts seek to establish, through two different projects, the presence of a broad group of new world hantaviruses including North-American variants such as Sin Nombre Virus (SNV), New York virus (NYV), Monnongahela virus (MGLV) and Prospect Hill virus (PHV); Hantaviruses likely to be present in Mexico such as Montano virus (MTNV), Huitzilac virus (HUIV), Carrizal virus (CARV), El Moro Canyon virus (ELMCV), Limestone Canyon virus (LSCV), Catacamas (CATV), Black Creek Canal virus (BCCV) and Bayou virus (BAYV); as well as Central and Southamerican Hantavirus such as Andes virus (ANDV) and Choclo (CHOV). In addition, recent efforts are underway to characterise the presence of the old world hantavirus, Seoul virus (SEOV) among wild rat populations as well as in domesticated laboratory rats. Our reserach interest aim to characterize specific hantavirus prevalece in Mexico, develop nucleic acid and serologic assays for their detection and for use in epidemiological surveillance.

Click on the link to access the documents of interest.

(Last updated: May 22, 2025. ©)


Presentations

The risk hantavirus pose for Mexico (detailed presentation). (Spanish), last update Jan 2024.

What you should know about Hantavirus Cardiopulmonary Syndrome (HCPS). (Spanish), last update feb 2023.

What you should know about Seoul hantavirus Haemorrhagic Fever with Renal Syndrome (HFRS). (Spanish), last update Jan 2024.



Brochures

What you should know about Hantavirus Cardiopulmonary Syndrome (HCPS). (Spanish), last update feb 2023.

What you should know about Seoul hantavirus Haemorrhagic Fever with Renal Syndrome (HFRS). (Spanish), last update feb 2023.



Infographs and images

Hantavirus rodent reservoir atlas. (Spanish), last update feb 2023.

Hantavirus infection viral load and antibody response kinetics. (English, Spanish), last update Feb 2023.



Forms

Hantaviral disease risk assessment interview.

This form is used to document the field collection of rodent specimens for ecological, epidemiological, and laboratory analysis. It captures essential data including capture location, species identification, sex, weight, and condition of the specimen, as well as any associated biological samples obtained. The information supports disease surveillance, biodiversity monitoring, and research on rodent-borne pathogens.

Download Spanish pdf document, v9.1, Jul 03, 2024.
Laboratory acquired SEOV infection KAP survey.

This form is used to document the field collection of rodent specimens for ecological, epidemiological, and laboratory analysis. It captures essential data including capture location, species identification, sex, weight, and condition of the specimen, as well as any associated biological samples obtained. The information supports disease surveillance, biodiversity monitoring, and research on rodent-borne pathogens.

Download Spanish pdf document, v9, Nov 28, 2023.
Rodent specimen collection form.

This form is used to document the field collection of rodent specimens for ecological, epidemiological, and laboratory analysis. It captures essential data including capture location, species identification, sex, weight, and condition of the specimen, as well as any associated biological samples obtained. The information supports disease surveillance, biodiversity monitoring, and research on rodent-borne pathogens.

Download Spanish or English pdf document, v3, Feb 11, 2016.
Bat specimen collection form.

This form is designed to record detailed information on the collection of bat specimens for research and surveillance purposes. It includes data fields for species identification, sex, age class, morphometric measurements, sampling site, and types of biological specimens collected. The form supports studies on bat ecology, zoonotic disease risk, and biodiversity within a One Health surveillance framework.

Download Spanish or English pdf document, v3, Feb 11, 2016.
Bat surveillance community report form.

This form enables members of the public, field personnel, and collaborating institutions to report sightings, roosts, or interactions involving bats that may be relevant to public health or ecological surveillance. Submitted data support ongoing efforts to monitor potential zoonotic risks, understand bat population dynamics, and inform evidence-based interventions within a One Health framework.

Download Spanish pdf document, version 3, Mar 28, 2022.
Rat Collection Form

Our lab's data collection form (PDF) standardizes the recording of morphometric, socio-economic, and geographic data from rats in rodent-borne disease surveillance, supporting epidemiological studies on population dynamics, disease transmission, and human exposure risks.

Download Spanish pdf document, Version 1, Jan 20, 2025.
Hantavirus project informed consent form.

This document provides researchers and participants with a comprehensive guide to the informed consent process for genomic studies conducted in our lab. It outlines ethical considerations, data handling procedures, and participant rights, ensuring transparency and adherence to regulatory standards. By clarifying responsibilities and expectations, this manual helps maintain the integrity of our research while safeguarding participants’ well-being and privacy.

Download Spanish pdf document, Version 3, Jun 24, 2024.



RNA-dependent RNA-Polymerase encoding large (L) segment sequence alignments and phylogenetics

Hantavirus L segment nucleotide sequence bootstrap tree (pdf format). (English), last update May 2022.

Hantavirus L segment nucleotide sequence bootstrap tree (png format). (English), last update May 2022.

Hantavirus L segment nucleotide sequence bootstrap tree (FigTree format). (English), last update May 2022.

Hantavirus L segment nucleotide sequence alignments (fasta format). (English), last update May 2022.

Seoul virus (SEOV) L segment nucleotide sequence unanimity alignments (pdf format). (English), last update May 2022.

Hantavirus L segment targetting oligonucleotides used for SEOV screening (pdf format). (English), last update May 2022.

Hantavirus RdRp-encoding, large(L) segment oligonucleotide primer map (pdf format). (English), last update May 2022.

Seoul (SEOV) hantavirus L-segment artificial gene sequence. (English), last update Feb 2023.



Nucleoprotein encoding small (S) segment sequence alignments and phylogenetics

Published hantavirus S segment targeting oligonucleotide primers (pdf format). (English), last update May 2022.

Hantavirus S segment primer map and sequence coverage (pdf format). (English), last update May 2022.

American hantavirus S segment nucleotide alignment (txt format). (English), last update May 2022.

American hantavirus S segment oligo specificity table (pdf format). (English), last update May 2022.

American hantavirus S segment phylogeny Old World outgroup (pdf format). (English), last update May 2022.

American hantavirus S segment phylogeny 88 taxa 433 sites (pdf format). (English), last update Feb 2023.

American hantavirus S segment phylogeny 88 taxa 433 sites (FigTree format). (English), last update Feb 2023.

American hantavirus Clade 1 (SNV) S segment nucleotide alignments (pdf format). (English), last update Feb 2023.

American hantavirus Clade 2 (MTNV) S segment nucleotide alignments (pdf format). (English), last update Feb 2023.

American hantavirus Clade 3 (HUIV) S segment nucleotide alignments (pdf format). (English), last update Feb 2023.

American hantavirus Clade 4 (OROV) S segment nucleotide alignments (pdf format). (English), last update Feb 2023.

Sin Nombre virus (SNV) hantavirus S-segment artificial gene sequence. (English), last update Feb 2023.

El Moro Canyon virus (ELMCV) hantavirus S-segment artificial gene sequence. (English), last update Feb 2023.

Limestone Canyon virus (LSCV) hantavirus S-segment artificial gene sequence. (English), last update Feb 2023.

Muleshoe virus (MULV) hantavirus S-segment artificial gene sequence. (English), last update Feb 2023.

Huitzilac virus (HUIV) hantavirus S-segment artificial gene sequence. (English), last update Feb 2023.

Playa de Oro virus (OROV) hantavirus S-segment artificial gene sequence. (English), last update Feb 2023.

Montano virus (MTNV) hantavirus S-segment artificial gene sequence. (English), last update Feb 2023.

American hantavirus species specific PCR-SSP oligonucleotide sequences (jpg format). (English), last update Aug 2023.

American hantavirus species specific PCR-SSP oligonucleotide specifications (jpg format). (English), last update Aug 2023.

American hantavirus clade specific PCR-SSP oligonucleotide specifications (jpg format). (English), last update Aug 2023.

American hantavirus clade specific PCR-SSP oligonucleotide sequences (jpg format). (English), last update Aug 2023.