| Oligonucleotide primers used for sequencing (supplementary material).
Oligonucleotide primer pairs used for subfragment amplification
of full-length influenzavirus gene segments. |
 |
Sampling of isolates subjected to nucleotide sequencing.
Number of cases sampled (grey columns) and those testing positive
for the A(H1N1) 2009 pdm strain (black columns) during the 2009-2010
epidemiological year. Arrows indicate the dates in which the sequenced
samples were collected. |
 |
Date of emergence of most recent common ancestor and mutation rates.
Date of emergence of most common ancestor and mutation rate for
the proteins encoded by each gene segment. Lines indicate 95% CI
and ticks indicate median, median mutation rate given as nucleotide
site substitituons per year (s/s/y x10-3) with 95% CI min-max in
parentheses. |
 |
Crystallographic distribution of HA and NA polymorphisms.
Three-dimensional surface map of haemagglutinin (panels A and B)
and neuraminidase (panel C) protein polymorphisms seen in ≥5% (red)
or <5% (yellow) of the unique Mexican sequences. Detail of NA active
site polymorphisms shown in panel D. Non-polymorphic background
is shown in greena. |
 |
Mexican pandemic influenza virus nucleotide clade diversity phylograms.
Mexican influenza virus nucleotide sequence radial cladograms.
|
 |
Evolution of Mexican pandemic influenza virus HA protein diversity.
Mexican influenza virus HA sequence clade evolution. |
 |
Mexican pandemic influenza virus protein sequence alignments.
Segment 1, Polymerase Subunit B2.
|
Mexican pandemic influenza virus nucleotide sequence FigTree cladograms (Note: Files will not display on browser, download link and view with FigTree).
Segment 1, Polymerase Subunit B2.
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